Nitrogen monoxide or nitric oxide is a compound of the chemical formula in the form of NO which serves as an intracellular signaling molecule in mammals including humans by modulating the form of blood flow, thrombosis, and neural activity. Molecules of nitric oxide are also often produced by pollutants from secondhand smoke, vehicles, and others, so it is often considered to be toxic and highly reactive. However, the use of nitric oxide gas in low concentrations is also beneficial for the treatment of pulmonary hypertension in newborns, received approval from the FDA. That is why there are supplements that can help someone to produce nitric oxide molecules in his or her body.
In addition, nitric oxide can be produced by neurons during 80 years in the human brain without causing toxic effects, levels of NO which are quite necessary for the body to nourish the liver from ischemic damage due to sepsis, but the production of NO during an ischemic brain damage the same neurons.